Oral sialadenoma papilliferum with kras mutation in a patient with linear nevus sebaceous syndrome| Pathologica - Journal of the Italian Society of Anatomic Pathology and Diagnostic Cytopathology
Vol. 116: Issue 4 - August 2024
DOI: 10.32074/1591-951X-992
Case reports
Published: 2024-09-30
download
PDF

Oral sialadenoma papilliferum with kras mutation in a patient with linear nevus sebaceous syndrome

Pathology Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna, Bologna, Italy
Oral and Maxillofacial Surgery Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna, Department of Biomedical and Neuromotor Sciences DIBINEM, Univeristy of Bologna
Oral and Maxillofacial Surgery Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna, Department of Biomedical and Neuromotor Sciences DIBINEM, Univeristy of Bologna
Oral and Maxillofacial Surgery Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna, Department of Biomedical and Neuromotor Sciences DIBINEM, Univeristy of Bologna
Solid Tumor Molecoular Pathology Laboratory, IRCCS Azienda Ospedaliero Univeristaria di Bologna, Bologna, Italy
Microbiology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, 40138, Italy.
Microbiology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, 40138, Italy.
Unit of Anatomic Pathology, Bellaria Hospital, Department of Biomedical and Neuromotor Sciences DIBINEM, University of Bologna, Bologna, Italy
Linear nevus sebaceous syndrome sialoadenoma papilliferum KRAS mutation

Abstract

Linear nevus sebaceous syndrome (LNSS) is a rare neurocutaneous syndrome part of the epidermal nevus syndromes group, characterized by the presence of sebaceous nevi and other extracutaneous lesions genetically related to RAS family gene mutations. Sialadenoma papilliferum (SP) is a rare benign intraoral neoplasm which is usually BRAF or HRAS mutated. We report a case of a young female girl diagnosed with a LNSS who developed a SP which had a KRAS mutation. This is the first case of SP with a KRAS mutation in the context of a LNSS.

Affiliations

$authorString->getOrcid() =>

$authorString->getFullName() => Giulia Querzoli

$authorString->getUrl() =>

Giulia Querzoli

Pathology Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna, Bologna, Italy
non esiste orcidID ""

$authorString->getOrcid() =>

$authorString->getFullName() => Giovanni Badiali

$authorString->getUrl() =>

Giovanni Badiali

Oral and Maxillofacial Surgery Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna, Department of Biomedical and Neuromotor Sciences DIBINEM, Univeristy of Bologna
non esiste orcidID ""

$authorString->getOrcid() =>

$authorString->getFullName() => Francesco Vitali

$authorString->getUrl() =>

Francesco Vitali

Oral and Maxillofacial Surgery Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna, Department of Biomedical and Neuromotor Sciences DIBINEM, Univeristy of Bologna
non esiste orcidID ""

$authorString->getOrcid() =>

$authorString->getFullName() => Achille Tarsitano

$authorString->getUrl() =>

Achille Tarsitano

Oral and Maxillofacial Surgery Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna, Department of Biomedical and Neuromotor Sciences DIBINEM, Univeristy of Bologna
non esiste orcidID ""

$authorString->getOrcid() =>

$authorString->getFullName() => Dario De Biase

$authorString->getUrl() =>

Dario De Biase

Solid Tumor Molecoular Pathology Laboratory, IRCCS Azienda Ospedaliero Univeristaria di Bologna, Bologna, Italy
non esiste orcidID ""

$authorString->getOrcid() =>

$authorString->getFullName() => Liliana Gabrielli

$authorString->getUrl() =>

Liliana Gabrielli

Microbiology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, 40138, Italy.
non esiste orcidID ""

$authorString->getOrcid() =>

$authorString->getFullName() => Simona Venturoli

$authorString->getUrl() =>

Simona Venturoli

Microbiology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, 40138, Italy.
non esiste orcidID ""

$authorString->getOrcid() =>

$authorString->getFullName() => Maria Pia Foschini

$authorString->getUrl() =>

Maria Pia Foschini

Unit of Anatomic Pathology, Bellaria Hospital, Department of Biomedical and Neuromotor Sciences DIBINEM, University of Bologna, Bologna, Italy
non esiste orcidID ""

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Copyright

© Società Italiana di Anatomia Patologica e Citopatologia Diagnostica, Divisione Italiana della International Academy of Pathology , 2024

How to Cite

[1]
Querzoli, G., Badiali, G., Vitali, F., Tarsitano, A., De Biase, D., Gabrielli, L., Venturoli, S. and Foschini, M.P. 2024. Oral sialadenoma papilliferum with kras mutation in a patient with linear nevus sebaceous syndrome. Pathologica - Journal of the Italian Society of Anatomic Pathology and Diagnostic Cytopathology. 116, 4 (Sep. 2024), 254-257. DOI:https://doi.org/10.32074/1591-951X-992.
  • Abstract viewed - 0 times
  • PDF downloaded - 0 times